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Sunday, 24 May 2015

Study: Alcohol and oxytocin work on brain in similar ways

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© Shutterstock

    
Researchers at the University of Birmingham have highlighted significant similarities between the behavioural effects of oxytocin and alcohol.

The research, published in , draws on existing studies into the two compounds and details the similarities between the effects of alcohol and the 'love hormone', oxytocin, on our actions. The team warn that the oft-used nickname hides the darker side of oxytocin, and claim that it bears more semblances with the effects of alcohol than previously thought.

Oxytocin is a neuropeptide hormone produced in the hypothalamus and secreted by the posterior pituitary gland. It has long been established as playing a significant role in childbirth and maternal bonding. More recently it has been identified as a brain chemical with a key role in determining our social interactions and our reactions to romantic partners -- hence its nickname of 'the love hormone'.

Oxytocin increases prosocial behaviours such as altruism, generosity and empathy; while making us more willing to trust others. The socio-cognitive effects come about by suppressing the action of prefrontal and limbic cortical circuits -- removing the brakes on social inhibitors such as fear, anxiety and stress.

Dr Ian Mitchell, from the School of Psychology at the University of Birmingham, explained, "We thought it was an area worth exploring, so we pooled existing research into the effects of both oxytocin and alcohol and were struck by the incredible similarities between the two compounds."

"They appear to target different receptors within the brain, but cause common actions on GABA transmission in the prefrontal cortex and the limbic structures. These neural circuits control how we perceive stress or anxiety, especially in social situations such as interviews, or perhaps even plucking up the courage to ask somebody on a date. Taking compounds such as oxytocin and alcohol can make these situations seem less daunting."

The team acknowledge that the ability to inhibit anxieties could explain the temptation to summon a little 'Dutch courage' -- particularly in the context of social situations such a first date. Dr Steven Gillespie said, "The idea of 'Dutch courage' -- having a drink to overcome nerves -- is used to battle those immediate obstacles of fear and anxiety. Oxytocin appears to mirror these effects in the lab."

When administered nasally, oxytocin appears to closely mirror the well-established effects of alcohol consumption. However the researchers warn against self-medicating with either the hormone or a swift drink to provide a little more confidence in difficult moments.

Alongside the health concerns that accompany frequent alcohol consumption, there are less desirable socio-cognitive effects that both alcohol and oxytocin can facilitate. People can become more aggressive, more boastful, envious of those they consider to be their competitors, and favour their in-group at the expense of others. The compounds can affect our sense of fear which normally acts to protect us from getting into trouble and we often hear of people taking risks that they otherwise wouldn't.

A dose of either compound can further influence how we deal with others by enhancing our perception of trustworthiness, which would further increase the danger of taking unnecessary risks.

Dr Gillespie added, "I don't think we'll see a time when oxytocin is used socially as an alternative to alcohol. But it is a fascinating neurochemical and, away from matters of the heart, has a possible use in treatment of psychological and psychiatric conditions. Understanding exactly how it suppresses certain modes of action and alters our behaviour could provide real benefits for a lot of people. Hopefully this research might shed some new light on it and open up avenues we hadn't yet considered."

Story Source:

The above story is based on materials provided by University of Birmingham.

Journal Reference:

  1. Ian J. Mitchell, Steven M. Gillespie, Ahmad Abu-Akel. Similar effects of intranasal oxytocin administration and acute alcohol consumption on socio-cognitions, emotions and behaviour: Implications for the mechanisms of action. , 2015; 55: 98 DOI: 10.1016/j.neubiorev.2015.04.018

Islamic State kills 400, mostly women & children, in Palmyra

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© Reuters / Nour Fourat
Historical city of Palmyra, Syria.

    
Islamic State militants have killed at least 400 people in Syria's ancient city of Palmyra, mostly women and children, Syrian state television said Sunday, citing residents.

According to Reuters, opposition activists on social media claimed that hundreds of bodies were in the streets of the city.

Islamic State militants have entered Syria's historic city of Palmyra, a UNESCO landmark, earlier this week after gaining full control over the city. The UN human rights office said Thursday that one-third of Palmyra's population of 200,000 have fled the city, although there have also been reports of government forces preventing civilians from leaving until they had abandoned the town themselves.

UNESCO describes Palmyra as a city of "outstanding universal value," an "oasis in the Syrian desert" northeast of Damascus. "From the 1st to the 2nd century, the art and architecture of Palmyra, standing at the crossroads of several civilizations, married Greco-Roman techniques with local traditions and Persian influences."

Another botched rape case: Baton Rouge woman drugged, sexually assaulted and photographed; no charges filed against rapist

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Lyndsi Lambert

    
Lyndsi Lambert said she was convinced that in Sgt. Jacques Jackson's mind, her entire case was riding on smartphone photos.

If the device taken from the man that she accused last September of drugging and sexually assaulting her contained the sexually explicit pictures that she remembers him taking of her, there would be sufficient evidence to bring charges.

The pictures were critical to the case, because the sheriff's office's strategy was to charge the man with video voyeurism, a more straightforward crime to prove than sexual assault.

Lambert felt that Jackson, the East Baton Rouge Sheriff's Office sergeant leading the investigation, was too focused on the photos and not enough on the potential for rape charges. Her hopes for a quick arrest were dashed, she said, when Jackson called several days after taking the man's phone to inform her that no photos of her from that night were on it.

Unless the man distributed the photos somewhere, she says Jackson told her, the police couldn't substantiate her claims.

The man told police he deleted the photos after Lambert's sister questioned him about them, and because they were "dark," according to the case file.

Lambert said she thought Jackson was too quick to accept that explanation. The man's statement confirmed that sexual pictures were taken, something Lambert said she would not have allowed.

She questioned how the photos could have been too dark if the only reason she knew they were taken was because she saw a flash through her closed eyelids. She questioned whether data recovery specialists could recover the deleted photos; Jackson assured her everything that could be done had been done. She questioned whether a device other than the iPhone had been used to take the pictures.

"We can't just take every device in his house," Jackson is heard telling her at a meeting in October she recorded.


***

In the Oct. 15 recording provided by Lambert, Jackson indicates he doesn't feel there's enough probable cause to arrest the man for rape, in part because of sexually charged text messages Lambert and the man exchanged earlier that day.


The night before the alleged rape, Lambert said, she and the man had oral sex; they had on one previous occasion had sexual intercourse. On the evening when they had oral sex, the man had choked her and spanked her hard enough to bruise her buttocks, she said. She sent him text messages the next day, the case file confirms, telling him she liked it and wanted to do it again.

She also texted him about plans they had made to go to Kinky Salon in New Orleans, which the case file describes as "a swingers club." (Kinky Salon's website specifically rejects that label, describing itself instead as "an inclusive sex-positive community" that hosts parties providing a "safe space for people of all persuasions to explore their sexuality without fear of judgment.")

Lambert said she had never attended Kinky Salon before, but discussed with the man the possibility that they would encounter group sex at the event. According to the case file, the man characterized that conversation differently, telling investigators that Lambert told him "she wanted to have several guys gang bang her." Lambert says she told Jackson that she never said that, but her denial is not included in the report.

Said Lambert of the case file: "I felt like the language used and the tone was really skewed against me. After I read the whole 38-page document, I just felt sick."

Lambert said she was forthright with police about the sexual texts and her prior sexual relations with the accused. Her sexual proclivities are not relevant to what she alleges happened at the apartment that night, she said. But the sheriff's office, she felt, looked at those text messages and the couple's sexual history as "equaling consent. ... Consent doesn't work that way," she said.


Leah Foster, clinical director of trauma recovery services for the New Orleans Family Justice Center, said consent is something that must be given "before and during each and every sexual encounter.

"Consent doesn't happen once and it's done," Foster said. "It is an ongoing conversation that needs to happen as each sexual encounter unfolds. Just because someone agreed to sex once doesn't mean they will agree again."

If the events of Sept. 25, 2014, unfolded as Lambert alleges, the incident would appear to fit the definition of "simple rape" under Louisiana statute 14:43. That law classifies as simple rape a forcible sex act "when the victim is incapable of resisting or of understanding the nature of the act by reason of a stupor or abnormal condition of mind produced by an intoxicating agent or any cause and the offender knew or should have known of the victim's incapacity."

Prior consensual sex with a rape suspect should have no bearing on whether charges are brought, a sheriff's office spokeswoman said. But it can make rape exam results less useful, compared to cases where the suspect is not known and DNA evidence can help identify them, or there is a question of whether or not any sex occurred.

It can also complicate efforts to prosecute, given the differing sexual attitudes of jurors. The key in these types of cases, said Michael Moore, president of the National District Attorneys Association, is to collect as much corroborating evidence as possible.

Investigators did find some other evidence in Lambert's case, but nothing that decisively resolved the conflicting accounts of what occurred in the man's apartment.

One witness who saw Lyndsi Lambert incapacitated at around midnight in the parking lot of the bar was her sister, Jana -- which Lambert says should be considered as evidence she was too drunk or drugged to consent.

The sheriff's office interviewed two employees at Lakeside Daiquiris & Grill, who said they remembered seeing Lambert and the man, according to the case file. They said Lambert appeared to be drunk or high when she arrived at the bar -- which she adamantly denies -- but otherwise confirmed a basic timeline of when the couple left and how much they drank.

The case file doesn't indicate whether the officer asked the employees about Lambert's condition when she left the bar that evening, but it does state they knew Lambert's date as a frequent patron at the bar.

The video surveillance at the bar was inoperable that night, the owner told police.

No one, Lambert says, has been able to provide a satisfactory answer to one key question: If no crime occurred, as the man told police, why did he insist that her sister pick her up at the bar parking lot, rather than at his apartment?

***

Despite the holes in the case, Lambert continued to press for charges. To her surprise, given their stated lack of confidence in the evidence, the sheriff's office wrote a warrant for the man's arrest for rape in October.

The warrant was delivered Oct. 21 to 19th Judicial District Court Judge Richard "Chip" Moore. He did not find probable cause and declined to sign it, according to the sheriff's office. Moore didn't return calls requesting comment for this story.

Lambert said the sheriff's office told her that once the judge had declined to sign the warrant, the investigation was pretty much over unless new evidence surfaced. So Lambert continued to push it forward on her own.

She shifted some of her attention to a civil suit she filed in family court Oct. 9, requesting a restraining order against the man and to stop him from sharing any pictures he might have.

In mid-February, after months of continuances, she expected to be subpoenaed for a deposition. Advised by a lawyer from Sexual Trauma Awareness and Response Center that anything she said could be used against her in any future court proceedings -- and fearing that if she lost the civil case, she'd have to pay for the man's legal and attorney fees -- she dropped the suit.

"Based on how everything else had gone up until this point," she said, "I had no reason to believe I was going to win this protective order."

Meanwhile, she continued to pursue her fight at the sheriff's office. Lambert says she contacted Internal Affairs and informed them of her intent to file a complaint against Jackson. She spoke out at a Take Back the Night rally, publicly criticizing her treatment by investigators. She brought her complaints to the Louisiana Inspector General's Office.

Each time she voiced her concerns, she said, the case seemed to take another step forward -- but then another step back. Based on her conversations with the sheriff's office, she said she was under the impression multiple times that her case had stalled or been closed, but as she continued to press officials, they would assure her it was active again.

For example, a few days after Lambert spoke out at Take Back the Night, Jackson got a search warrant to search the man's other electronic devices for photos, according to the case file -- despite him telling her a week earlier that wouldn't be possible. That search, which occurred a month after the sheriff's office's initial interview with the suspect, turned up empty.

"Why do victims who speak out suddenly get further into their investigation?" she asked. "Had I not spoken out, it would have just been case closed. Is it the responsibility of a victim to hold law enforcement accountable, to make sure that her rapist is charged? That's a heavy burden."

***

On Oct. 29, more than a week after the case was sent to the judge, Jackson -- who had opted not to send Lambert's bloodwork to the crime lab the day after the alleged rape -- arranged to have a hair sample from Lambert tested for date rape drugs, the case file shows.

Lambert refused to provide the sample, declining, she said, because her research indicated hair samples are typically used to test for repetitive drug use, not the presence of a date rape drug. Although denying drug use, Lambert said she was concerned Jackson was seeking evidence to discredit her.

Moreover, Lambert said she worried that if the test for a rape drug came back negative, a defense attorney could use that to discredit her story.

Dr. Randall Brown, a Baton Rouge forensic medical examiner who specializes in women's sexual assault cases, said that hair testing for date rape drugs is newer technology that is "not quite ready for widespread use." A single instance is difficult to detect, Brown said, unless there has been a "fairly large ingestion."

***

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© Kathleen Flynn, NOLA.com/The Time Picayune
The East Baton Rouge Sheriff's Office took Lyndsi Lambert's rape complaint on Sept. 26, 2014.

    
In February, after Lambert had been in contact with the Inspector General's office, she said, Major Bryan White of the East Baton Rouge Sheriff's Office met with Lambert and informed her that her case had been sent to the East Baton Rouge District Attorney's office, which was pursuing it further.

Lambert walked away from that meeting believing that the DA's office was going to present her case to a grand jury. But Sue Bernie, the assistant district attorney handling the case, said that was a "miscommunication": There was never a plan to send it to a grand jury, which would be a very unusual step for a case where a judge had declined to sign an arrest warrant.

In Lambert's meeting with White, which she recorded, White acknowledged the sheriff's office made mistakes in its handling of the case, and promised more oversight for investigating officers.

"Some of the things that happened are inexcusable, you're correct," White says on the recording of the February meeting. "But with that being said, when it was found out that we obviously didn't do our due diligence, it's being done. The case is not over."

A vial of blood taken during Lambert's rape exam and stored for nearly five months was finally -- on Feb. 19 -- sent to the State Police crime lab for toxicology testing, according to the case file. The results came back negative.

Lambert says she wasn't surprised, because she knew there was a good chance any drugs had left her system by the time she was tested. But even so, when sheriff's deputies gave her the news, "as soon as I closed the door my knees hit the ground and I just started wailing," she said. "It was really hard."

As the investigation dragged on, Lambert said she became depressed and considered getting on anti-depressive medication. She was having trouble sleeping. She took time off from her job. She felt nauseous whenever she saw a sheriff's office car, she said. She moved out of her place, worried that the man knew where she lived.

In February, the investigation still languishing, Lambert contacted a NOLA.com | The Times-Picayune reporter and expressed her desire to share her story. She said she hoped the media attention would help other people who report sexual assaults and perhaps jump-start the investigation. But her hopes for an eventual arrest were dashed on April 30 when Lambert's case was closed -- this time, apparently, for good -- 216 days after she reported being drugged and raped.

The sheriff's office conceded that it made mistakes, but indicated an absence of supporting evidence is what made this case impossible to prosecute.

"From the evidence gathered from witness statements and lab results, detectives do not feel the outcome of the case would change (even if the investigation had been handled differently)," sheriff's office spokeswoman Casey Rayborn Hicks said. "The facts of the case have been reviewed by a judge and additionally by the district attorney's office. Sufficient evidence was not present to warrant an arrest."

The man's attorney, Franz Borghardt, echoed the sheriff's office's sentiments in a statement.

"Having had the chance to review the case file, and all the discovery, it appears and it is our belief that someone made an allegation of a crime, the case was thoroughly investigated by the police, and ultimately a judge found no probable cause to merit an arrest warrant," he said. "This is the system working."


Lambert thinks the criminal case is now over, but she said she is far from finished. She wants to get involved in policy work related to sexual assault issues, and she's considering going to law school. Although the criminal justice system has drawn its own conclusion about her case, she feels that she was victimized twice.

"If I can't get my own rapist behind bars," she said, "maybe I could use my experience to help get other rapists behind bars."

The East Baton Rouge Sheriff's Office recently transferred Jackson out of General Investigations, which typically handles sexual assault investigations, to a different division in the sheriff's office. Asked whether the transfer was a response to his handling of Lambert's case, Hicks said: "We transfer employees all the time depending on best fit and personnel need."

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Memorial day storms threatens more than half the U.S.

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Showers and thunderstorms threaten to interfere with Memorial Day festivities across more than half of the United States.

That does not mean that half of the picnics, parades and other outdoor events throughout the nation will not be able to go on as scheduled.

Monday will not be a complete washout in most communities being threatened by showers and thunderstorms. There will still be stretches of dry weather.

Residents should monitor their local forecast pages to determine the best time to schedule outdoor plans. On the actual holiday, a close eye will have to be kept on the sky and AccuWeather MinuteCast® to know when to move indoors.

Widespread severe weather is not a concern on Monday, but lightning is.

"While only a small number of storms become strong enough to produce damaging winds, large hail and tornadoes, every thunderstorm produces lightning," stated AccuWeather.com Brian Lada.

"Lightning is one of nature's deadliest phenomena, claiming roughly 55 to 60 lives every year across the United States and injuring hundreds more," added Lada.

The most active parts of the nation in terms of thunderstorms will lie from Texas and the northern Gulf Coast states to the Midwest and St. Lawrence Valley and across the northern Plains and Intermountain West.

A large corridor of showers and thunderstorms will be found on Monday from the Gulf Coast to the Midwest with steamy air in place and a storm system located over the Upper Midwest.

The morning hours will be more active than the afternoon around Chicago and St. Louis.

On the cool side of the storm, periods of rain will dampen the northern Plains--Fargo, North Dakota, included. Just south of this zone, thunderstorms will return to Nebraska with a few of the thunderstorms becoming strong in the afternoon.

The greatest concern for the thunderstorms to be heavy and trigger flash flooding lies from Texas to the lower Mississippi Valley, home to Shreveport, Louisiana.

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In addition to flooding downpours, the threat also exists for some of the thunderstorms in central and eastern Texas to turn severe with damaging winds, hail and an isolated tornado. San Antonio, Dallas and Houston are among the communities at risk.

These violent thunderstorms will eventually bring yet another round of flooding downpours to the lower Mississippi Valley at night.

Meanwhile, the thunderstorms set to develop from the eastern Gulf Coast and Georgia to the eastern Tennessee Valley will mainly be limited to the afternoon and spottier in nature. Most of the Carolinas will stay dry.

Along the leading edge of the surging warm and humid air, a steadier band of rain and thunderstorms threatens to cause more significant disruptions to holiday plans across the upper Great Lakes.

The eastern extent of this wet weather will nose into the St. Lawrence Valley, while the rest of the Northeast and mid-Atlantic remain dry and turn warmer.

Two other storm systems will work to keep a large part from the Rockies to the Cascades and Sierra unsettled with showers and thunderstorms. The afternoon hours will be the most active time of the holiday.

Anyone planning to spend Monday at a national park or forest, including Yellowstone or Rocky Mountain, should have a plan in place of where to seek shelter during a thunderstorm.

As soon as thunder is heard, the risk of being struck by lightning is present.

The Desert Southwest and the immediate West Coast should escape wet weather on Memorial Day. In the Southwest, that means residents will have to remain diligent when participating in some holiday festivities to avoid starting a brush or wildfire.

Away from the contiguous United States, showers will dot Alaska and a few windward communities on Hawaii this Memorial Day. The shower chance will come after Fairbanks, Alaska, experiences a rare feat of recording a high greater than Phoenix on Saturday.

Wayward bird turns up on the wrong side of the Rockies in Lodi, California

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A Baltimore Oriole (though not the one seen recently near Lodi) at Emmenegger Nature Park in St. Louis

    
Most often, the only Baltimore Orioles you'll find in Northern California are the 6-foot-tall variety that migrate to the Oakland Coliseum a couple of times each year.

Members of Stockton's Audubon Society, however, are excited about a Baltimore Oriole — a bird, not a baseball player — spotted recently at Westgate Landing Regional Park just north of Highway 12, in the Delta west of Lodi.

The oriole was first seen by Lodi birders Dave and Pat Croft on May 15. Other birders have since come from as far away as Palo Alto to get a look, Dave Croft said.

The distinguished visitor is a very loud fellow, Croft said, and is quite active flying back and forth between the trees in the park.

"He might be singing for a mate," Croft said. "Who knows?"

The find is rare, said well-known local birder David Yee.

"Here in San Joaquin County, this is only the second time a Baltimore has ever been found," Yee wrote in an email. "The first was back in the early '80s. ... There are probably less than 10 records total of Baltimore Orioles for the entire Central Valley, so it is a rarity indeed."

Baltimore Orioles are typically found east of the Rockies, but they do nest as far west as central Alberta in Canada.

And, like any bird that migrates long distances, they sometimes stray far from their typical range. Often, young birds will simply go the "wrong way" and fly west toward California, instead of east where the majority of the population goes, Yee said.

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Baltimore Oriole - Species range map

    

Huge apocalyptic thunderstorm cloud engulfs San Luis Potosi, Mexico

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Thunderstorm cloud over San Luis Potosi

    
This apocalyptic thunderstorm cloud suddenly appeared in the sky of San Luis Potosi surpising its residents!

That's really a giant cumulonimbus!

This type of giant and angry clouds are more than common in arid or desert areas. But not in San Luis Potosi!

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Nepal landslides spark fear of flash floods

© Philippe Lopez/AFP/Getty Images
As survivors of the Nepal earthquakes struggle with the aftermath, a landslide has caused fears of flash flooding.

    
Villagers evacuated after landslips block fast-flowing river, with emergency workers hoping to drain water masses before they destroy scores of homes

Thousands of people have been told to evacuate their homes in Nepal after massive landslides blocked a river in the west of the country, sparking fears of flash flooding.

Two powerful earthquakes devastated Nepal on 25 April and 12 May, killing nearly 8,700 people and injuring 16,800 others.

Authorities fear tremors could unleash a flash flood that could destroy dozens of villages in the remote Myagdi district, 80 miles (130km) north-west of Kathmandu, the capital.

Emergency workers are hoping to drain the lake created behind the debris now blocking the normally fast-flowing Kali Gandaki river.

Kamal Singh Bam, a spokesman for Nepal police, said at least 123 people had already been evacuated from areas flooded by the newly formed lake. "Luckily they are safe, but the water level has risen covering all the houses up to around a kilometre upstream of the landslide," Bam said.

Nepal's quake-shattered villages: 'there's nothing to stay for now'

Sesh Narayan Poudel, a senior bureaucrat, said at least 10 villages had been evacuated overnight. "The water level of Kali Gandaki flowing below the dam is dropping, and that's not a good sign," Poudel said.

Although police and army teams have reached the site, the threat of new tremors has prevented work to drain the lake and ease the pressure on the natural dam. Continuing aftershocks and the effect of the first major earthquake have left many areas in Nepal unstable.

"Once the landslides have stopped, our technical team in the area will assess the situation, and once we get their report we can try and get the water flowing again," Rishiram Sharma, head of the department of hydrology and meterology, said.

There have also been warnings that natural dams holding back massive glacial lakes high in the Himalayas could have been damaged in the earthquake last month. If one such dam gave way, flood water could kill thousands and destroy huge numbers of homes.

Two lakes in particular - one close to Everest and the other about 18 miles (30km) from the mountain - have caused concern in the past. But specialists say that unless there is a further tremor with an epicentre close to the lakes, they are safe for now.

"We have assessed all the glacial lakes potentially under threat, but there is no any difference in the assessment before and after the earthquake," Sharma said.

There are 1,466 glacial lakes in Nepal, with 21 big enough to cause serious concern. Many are swollen with glacial meltwater as a result of climate change, scientists say.

Myagdi district, where the villagers were evacuated on Saturday night, is in the west of the south Asian country and some distance from the areas worst affected by last month's tremor.

Geologists say the case should be a "a wakeup call for the Nepal", especially with summer rains forecast. "With the coming monsoon it's sure that Nepal will see several such landslides," Ranjan Kumar Dahal, a geologist said.